However, testosterone in physiologic doses could even be useful in sufferers with angina , have higher ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and increases coronary blood flow in men with established coronary artery illness . Therefore, an interplay of endogenous elements of the patient’s threat profile as nicely as the testosterone dosing may be issues of whether or not opposed occasions happen. Erythrocytosis has been reported as a potential effect of testosterone, which could be helpful in patients with anemia.
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- Men with coronary artery disease have decrease levels of androgens than males with regular coronary angiograms.
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- Supraphysiologic doses of anabolic-androgenic steroids , which embrace more than 30 pure and synthetic derivatives of testosterone, may cause a large spectrum of clinical sequalae.
- Feller AA, Mylonakis E, Rich JD. Medical problems of anabolic steroids.
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Anabolic Steroids, Acute Myocardial Infarction And Polycythemia: A Case Report And Review Of The Literature
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Patients also may be taking concomitant stimulants, such as ephedra, which may confound knowledge and the potential for antagonistic occasions. It is in all probability going that the frequency of cardiac events is underreported within the medical literature. Moreover, testosterone has been used in the therapy of decreased muscle mass and bone density in addition to anemia. The function testosterone could play within the improvement of heart problems has more and more turn into the topic of current interest . Supraphysiologic doses of anabolic-androgenic steroids , which embody more than 30 pure and artificial derivatives of testosterone, may trigger a wide spectrum of scientific sequalae. Supplemental or physiologic doses of testosterone have observed expanded use in medical practice just lately. Other widespread potential adverse effects embrace infertility, hepatotoxicity, psychological abnormalities, and gynecomastia .
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The greatest risk of erythrocytosis occurs with injectable types of testosterone in contrast with transdermal preparations, particularly in supraphysiologic doses. An enhance of up to 44% of the baseline hematocrit has been reported . Anabolic androgenic steroid use has elevated over the previous decade, regardless of its potential for antagonistic results. They proceed for use by Olympic stage athletes, and have even spread to highschool level athletes, noncompetitive bodybuilders and recreational athletes (Sullivan et al 1998; Dhar et al 2007). Unfortunately, the data on the use of high dose anabolic steroids in people are primarily offered as case stories or small research that lack sufficient control groups. In addition, the information available within the literature doesn’t account for the steroid kind or dose, as neither may be known.
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